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Caviinae is a subfamily uniting all living members of the family Caviidae with the exception of the maras, capybaras and Kerodon. The subfamily traditionally contained the guinea pig-like forms along with the cursorially (running) adapted Kerodon. Molecular results suggest that the Caviinae as so defined would be paraphyletic and that Kerodon is more closely related to maras and capybaras than to other caviines (Rowe and Honeycutt, 2002). This led Woods and Kilpatrick (2005) to unite Kerodon and capybaras into the subfamily Hydrochoerinae within the Caviidae. These studies also suggest that Microcavia and Cavia are more closely related to one another than either is to Galea.

Animals are a major group of mostly multicellular, eukaryotic organisms of the kingdom Animalia or Metazoa. Their body plan eventually becomes fixed as they develop, although some undergo a process of metamorphosis later on in their life. Most animals are motile, meaning they can move spontaneously and independently. All animals are also heterotrophs, meaning they must ingest other organisms for sustenance.

Most known animal phyla appeared in the fossil record as marine species during the Cambrian explosion, about 542 million years ago.